Nintedanib 150mg Capsule | Buy Online in Pakistan

Nintedanib 150mg is a targeted oral therapy used in the management of serious progressive lung conditions. Sold under the brand names Ofev and Vargatef, it belongs to a class of medicines called tyrosine kinase inhibitors (TKIs). This guide covers everything you need to know before using this medication. Order now at dawailo.pk to get Nintedanib 150mg capsule online at your door step.

What Is Nintedanib 150mg Capsule?

Nintedanib 150mg is a soft gelatin capsule prescribed for adults suffering from chronic and life-threatening lung diseases. It works by blocking specific enzymes (tyrosine kinases) responsible for abnormal cell growth and fibrosis — the scarring process that progressively destroys lung tissue.

It is available as a prescription-only medicine and must be taken under the direct supervision of a qualified specialist.

Uses of Nintedanib 150mg

Idiopathic Pulmonary Fibrosis (IPF)

The primary use of Nintedanib is in treating Idiopathic Pulmonary Fibrosis (IPF) — a chronic condition where lung tissue becomes scarred and stiff, making it increasingly difficult to breathe. Nintedanib slows the rate of lung function decline in IPF patients, improving quality of life over time.

Systemic Sclerosis-Associated ILD

Nintedanib 150mg Capsule is also approved for Interstitial Lung Disease (ILD) associated with systemic sclerosis (SSc-ILD), a condition where autoimmune inflammation leads to progressive fibrosis.

Non-Small Cell Lung Cancer (NSCLC)

Under the brand Vargatef, Nintedanib is used in combination with docetaxel chemotherapy for the second-line treatment of locally advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) with adenocarcinoma histology.

Dosage & Administration

Recommended Dose

The standard recommended dose of Nintedanib is 150mg taken twice daily, approximately 12 hours apart — typically with the morning and evening meals.

How to Take It

• Swallow capsules whole with water — do not crush, chew, or open them
• Always take with food to reduce gastrointestinal side effects
• Maintain a consistent schedule every day
• Do not double the dose if a dose is missed — skip and resume the next scheduled dose

Dose Adjustments

Your doctor may reduce your dose to 100mg twice daily if you experience significant side effects. Never adjust your dose without medical guidance.

Side Effects of Nintedanib 150mg Capsule

Common Side Effects

• Diarrhoea (most frequently reported — occurs in up to 62% of patients)
• Nausea and vomiting
• Abdominal pain or stomach discomfort
• Loss of appetite and weight loss
• Elevated liver enzymes

Serious Side Effects

• Liver toxicity — regular liver function tests are required
• Bleeding — due to anti-angiogenic effects
• Gastrointestinal perforation — rare but serious
• Arterial thromboembolic events (e.g., heart attack or stroke)
• Embryo-foetal toxicity — must not be used during pregnancy

Precautions Before Taking Nintedanib

• Inform your doctor about any existing liver or kidney conditions
• Avoid if you are pregnant or breastfeeding
• Disclose all current medications — Nintedanib can interact with P-glycoprotein inhibitors and CYP3A4 inducers
• Regular liver function monitoring is essential throughout therapy

Where to Buy Nintedanib 150mg Capsule in Pakistan

You can order Nintedanib 150mg Capsule (Ofev / Vargatef) online with a valid prescription from Dawailo.pk — Pakistan’s trusted online pharmacy serving Karachi, Lahore, and Islamabad.

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